Clinical Trial to Evaluate the Safety and Immunogenicity of Ferritin Nanoparticles Expressing Native-like HIV-1 Envelope Trimers Followed by Boost With mRNA Lipid Nanoparticles Encoding a Native-like HIV-1 Envelope Trimer in Adults Without HIV

NCT05903339 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

36

Enrollment

NIH

Sponsor class

Conditions

Hiv

Interventions

DRUG: V3G CH848 Pr-NP1 60mcg
DRUG: 3M-052-AF 5mcg
DRUG: Alum 500 mcg
DRUG: V3G CH848 mRNA-Tr2 50mcg
DRUG: ACU-026-001-1 2.0mg
DRUG: V3G CH848 Pr-NP1 100mcg

Sponsor

National Institute of Allergy and Infectious Diseases (NIAID)