Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

NCT05993611 · clinicaltrials.gov ↗

PHASE1

Phase

SUSPENDED

Status

27

Enrollment

OTHER

Sponsor class

Stopped pending funding

Conditions

Chronic Graft Versus Host Disease
Hematologic and Lymphocytic Disorder
Steroid Refractory Graft Versus Host Disease

Interventions

PROCEDURE: Biopsy
PROCEDURE: Biospecimen Collection
BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy
PROCEDURE: Computed Tomography
PROCEDURE: Echocardiography
OTHER: Electronic Health Record Review
PROCEDURE: Leukapheresis
PROCEDURE: Lumbar Puncture
PROCEDURE: Magnetic Resonance Imaging
OTHER: Quality-of-Life Assessment
BIOLOGICAL: Tafasitamab
PROCEDURE: X-Ray Imaging

Sponsor

City of Hope Medical Center

Collaborators

[object Object]