Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

NCT06022939 · clinicaltrials.gov ↗

PHASE3

Phase

RECRUITING

Status

338

Enrollment

NETWORK

Sponsor class

Conditions

AL Amyloidosis

Interventions

PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation
PROCEDURE: Biopsy
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
DRUG: Bortezomib
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
DRUG: Daratumumab and Hyaluronidase-fihj
DRUG: Dexamethasone
PROCEDURE: Echocardiography
PROCEDURE: Magnetic Resonance Imaging
DRUG: Melphalan
PROCEDURE: Positron Emission Tomography
PROCEDURE: Stem Cell Isolation
OTHER: Survey Administration

Sponsor

SWOG Cancer Research Network

Collaborators

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