A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

NCT06630325 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

6

Enrollment

OTHER

Sponsor class

Stopped Loss of support.

Conditions

Advanced Breast Carcinoma
Advanced Malignant Solid Neoplasm
Advanced Ovarian Carcinoma
Advanced Pancreatic Carcinoma
Advanced Prostate Carcinoma
Advanced Sarcoma
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage III Pancreatic Cancer AJCC v8
Stage III Prostate Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8
Stage IV Prostate Cancer AJCC v8

Interventions

DRUG: Abemaciclib
PROCEDURE: Biopsy
PROCEDURE: Bone Scan
PROCEDURE: Echocardiography
DRUG: Exemestane
DRUG: Gemcitabine
DRUG: Letrozole
PROCEDURE: Multigated Acquisition Scan
DRUG: Osimertinib
DRUG: Pemetrexed
OTHER: Survey Administration
DRUG: Tamoxifen
PROCEDURE: Biospecimen Collection

Sponsor

OHSU Knight Cancer Institute

Collaborators

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