Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

NCT06834126 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

36

Enrollment

OTHER

Sponsor class

Conditions

Locally Advanced Rectal Adenocarcinoma
Stage II Rectal Cancer AJCC v8
Stage III Rectal Cancer AJCC v8

Interventions

PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
DRUG: Consolidation Therapy
PROCEDURE: Functional Magnetic Resonance Imaging
PROCEDURE: Gastrointestinal Endoscopy
PROCEDURE: Magnetic Resonance Imaging
DRUG: Papaverine
RADIATION: Radiation Therapy
PROCEDURE: Total Mesorectal Excision

Sponsor

City of Hope Medical Center

Collaborators

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