Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial

NCT07220187 · clinicaltrials.gov ↗

PHASE3

Phase

NOT_YET_RECRUITING

Status

102

Enrollment

NETWORK

Sponsor class

Conditions

Richter Syndrome
Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma
Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma

Interventions

PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
DRUG: Doxorubicin Hydrochloride
PROCEDURE: Echocardiography Test
PROCEDURE: Multigated Acquisition Scan
DRUG: Pirtobrutinib
PROCEDURE: Positron Emission Tomography
DRUG: Prednisone
BIOLOGICAL: Rituximab
BIOLOGICAL: Rituximab and Hyaluronidase Human
OTHER: Survey Administration
DRUG: Vincristine

Sponsor

SWOG Cancer Research Network

Collaborators

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