Biomarkers of Response to SEEG Thermocoagulation

Conditions

• Drug Resistant Epilepsy

Interventions

• OTHER: Quality of life questionnaires (QOLIE, EFIQUACEE for children), psychiatric questionnaires (NDDIE, GAD-7, PCL-5) at Visit 1 (V1), V5, V6 and V7
• OTHER: Resting state SEEG recording 30min before and 30 min after RFTC
• OTHER: Blood sample at Visit 1 (V1), V2, V4 and V5
• OTHER: SEEG electrodes tissue-traces sample at V3 (during SEEG electrodes ablation)
• OTHER: Multiparametric 3T MRI with gadolinium at V1, V4 and V5
• OTHER: Multiparametric 7T MRI at V1 and V5

Sponsor

Assistance Publique Hopitaux De Marseille

Collaborators

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