Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

NCT07405476 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

38

Enrollment

OTHER

Sponsor class

Conditions

Colon Carcinoma
Colorectal Carcinoma
Rectal Carcinoma
Stage I Colon Cancer AJCC v8
Stage I Colorectal Cancer AJCC v8
Stage I Rectal Cancer AJCC v8
Stage II Colon Cancer AJCC v8
Stage II Colorectal Cancer AJCC v8
Stage II Rectal Cancer AJCC v8
Stage III Colon Cancer AJCC v8
Stage III Colorectal Cancer AJCC v8
Stage III Rectal Cancer AJCC v8

Interventions

BIOLOGICAL: Zanidatamab
PROCEDURE: Resection
OTHER: Patient Observation
PROCEDURE: Echocardiography Test
PROCEDURE: Multigated Acquisition Scan
PROCEDURE: Endoscopic Procedure
PROCEDURE: Computed Tomography
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Biospecimen Collection
PROCEDURE: Biopsy Procedure
PROCEDURE: Digital Rectal Examination
OTHER: Electronic Health Record Review

Sponsor

Emory University

Collaborators

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