This regulation establishes tolerances for combined residues of chlorothalonil and its 4-hydroxy metabolite in or on Brassica, head and stem, subgroup 5A; ginseng; horseradish; lentil; okra; rhubarb; vegetable, cucurbit, group 9; vegetable, fruiting, group 8, except tomato; and yam, true. It also establishes a tolerance with regional registration for combined residues of chlorothalonil and its metabolite on persimmon and removes existing tolerances for combined residues of chlorothalonil and its metabolite on broccoli, brussels sprouts, cabbage, cauliflower, cucumber, melon, non-bell pepper, pumpkin, summer squash, and winter squash; as well as the time-limited tolerance on ginseng. These tolerances are no longer needed, since they are superseded by the new tolerances on Brassica, cucurbit and fruiting vegetables and the permanent tolerance on ginseng. Interregional Research Project Number 4 (IR-4) requested these tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA).