Topical Therapies for Treatment of Cervical Intraepithelial Neoplasia 2-3
Abstract
Develop and conduct a phase 1 clinical trial to assess the safety and acceptability of once-weekly self-administered intravaginal application of 5-flurouracil (5-FU) and imiquimod used on alternating weeks for up to 16 weeks in women aged 18-45 years with biopsy confirmed high-grade cervical intraepithelial lesions.
Key facts
- NIH application ID
- 10189431
- Project number
- 261201200031I-P00003-26100011-1
- Recipient
- UNIVERSITY OF ARIZONA
- Principal Investigator
- Sherry Chow
- Activity code
- N01
- Funding institute
- NIH
- Fiscal year
- 2020
- Award amount
- $225,296
- Award type
- —
- Project period
- 2017-09-15 → 2022-07-31