PROJECT SUMMARY The goal of this administrative supplement is to acquire an A100 GPU cluster. Capitalizing on the advances that we have made in the prior years of MIRA funding, this GPU cluster will not only accelerate our computational efforts but open exciting new opportunities. These include the ability to simulate, for the first time, the same condensate systems as in our experimental studies; GPU-accelerated methods for quantifying nonspecific interactions in condensates; and the sequence code for the conformational, dynamic, and binding properties of intrinsically disordered proteins. Pursuing these new opportunities will enable greater integration between our computational and experimental studies and elevate our research to new heights unforeseen two years ago when the MIRA renewal was written.