Assessing the feasibility and acceptability of a Time Restricted Feeding intervention among older adults with Mild Cognitive Impairment

NIH RePORTER · NIH · R61 · $508,385 · view on reporter.nih.gov ↗

Abstract

Obesity and related metabolic comorbidities have been associated with more than a 4-fold increased risk of incident cognitive impairment, including Alzheimer’s disease and related dementias (ADRD). Dysfunctional metabolic flexibility is increasingly recognized as a critical mechanism linking metabolic risk factors to risk of cognitive impairment, although few studies portable behavioral strategies to enhance metabolic function among individuals at risk for ADRD. The present study will examine the feasibility and acceptability of a 12-week time restricted feeding intervention among individuals with mild cognitive impairment (MCI). Changes in cognitive and metabolic function will also be examined.

Key facts

NIH application ID
10771264
Project number
5R61AG080615-02
Recipient
UNIV OF NORTH CAROLINA CHAPEL HILL
Principal Investigator
Patrick Josey Smith
Activity code
R61
Funding institute
NIH
Fiscal year
2024
Award amount
$508,385
Award type
5
Project period
2023-02-01 → 2026-01-31