SUMMARY – hIPSC-REPROGRAMMING AND CELL CULTURE MODULE The hIPSC-Reprogramming and Cell Culture module (IPSC-CC) is a specialized research unit dedicated to advancing both fundamental and translational vision research. This module is led by Drs. Chen and da Silva and aims to achieve three main goals. First, the module uses cutting-edge screening tools to assist researchers in the discovery of novel treatments and critical targets for improving eye health and development. Unbiased screening process is a fast and robust way for uncovering groundbreaking advancements in eye care. Second, the module offers expertise in human induced pluripotent stem cells (hIPSC) and retinal organoids. the module directors possess specialized knowledge in hIPSC reprogramming and differentiation of 3D retinal organoids, a leading biological tool revolutionizing the regenerative medicine field. These cells can be sourced from patients with eye diseases, offering new opportunities for studying eye diseases and potentially unlocking new therapeutic solutions. Finally, the module provides and oversees state-of-the-art facilities while instructing researchers in standard tissue culture techniques. Through collaborations with participating faculty and access to top-tier equipment, the hIPSC-CC module aims to elevate vision research to new heights.