Possession, Use, and Transfer of Select Agents and Toxins-Addition of SARS-CoV/SARS-CoV-2 Chimeric Viruses Resulting From Any Deliberate Manipulation of SARS-CoV-2 To Incorporate Nucleic Acids Coding for SARS-CoV Virulence Factors to the HHS List of Select Agents and Toxins
public-health · Centers for Disease Control and Prevention · Rule · Published 2021-11-17 · Effective 2021-11-17 · 86 FR 64075
Document
Document number
2021-25204
Federal Register citation
86 FR 64075
CFR reference
42 CFR 73
Type
Rule
Action
Interim final rule.
Category
public-health
Sub-agency
Centers for Disease Control and Prevention
Publication date
2021-11-17
Effective date
2021-11-17
HHS docket
Docket No. CDC-2021-0119
Abstract
The Centers for Disease Control and Prevention (CDC) located within the Department of Health and Human Services (HHS) is amending its select agents and toxins regulations to add SARS-CoV/SARS-CoV-2 chimeric viruses resulting from any deliberate manipulation of SARS- CoV-2 to incorporate nucleic acids coding for SARS-CoV virulence factors to the list of HHS select agents and toxins. HHS/CDC intends to regulate this agent and to require the regulated entity to obtain prior approval from CDC to conduct deliberate manipulation of SARS-CoV-2 to incorporate nucleic acids coding for SARS-CoV virulence factors because these chimeric viruses have the potential to pose a severe threat to public health and safety.