public-health · Centers for Disease Control and Prevention · Rule · Published 2024-12-26 · 89 FR 104888
Document
Document number
2024-30568
Federal Register citation
89 FR 104888
CFR reference
42 CFR 73
Type
Rule
Action
Notification of determination.
Category
public-health
Sub-agency
Centers for Disease Control and Prevention
Publication date
2024-12-26
Abstract
The Centers for Disease Control and Prevention (CDC), located within the Department of Health and Human Services (HHS), has determined that a previously excluded attenuated strain, Jun[iacute]n virus vaccine strain Candid No.1, has key attenuating mutations in the glycoprotein envelope at GP1 T168A and GP2 F427I. Revertants at either of these positions have increased pathogenicity and virulence. Therefore, Jun[iacute]n virus vaccine strain Candid No. 1 containing GP1 168T and/or GP2 427F is a select agent and is subject to the select agent and toxin regulations.