Possession, Use, and Transfer of Select Agents and Toxins; Regulation of an Attenuated Vaccine Strain of Venezuelan Equine Encephalitis Virus as a Select Agent
plant-animal-health · Animal and Plant Health Inspection Service · Rule · Published 2022-09-01 · Effective 2022-09-01 · 87 FR 53647
Document
Document number
2022-18990
Federal Register citation
87 FR 53647
CFR reference
9 CFR 121
Type
Rule
Action
Regulatory determination.
Category
plant-animal-health
Sub-agency
Animal and Plant Health Inspection Service
Publication date
2022-09-01
Effective date
2022-09-01
USDA docket
Docket No. APHIS-2022-0034
Abstract
We are notifying the public that the Animal and Plant Health Inspection Service (APHIS) has determined that the modified Venezuelan equine encephalitis virus (VEEV) strain TC-83(A3G), which is a modification to the attenuated strain VEEV TC-83, has demonstrated increased pathogenicity and lethality and that the strain has the potential to pose a severe threat to animal health or animal products. We are advising the public that VEEV strain TC-83(A3G) is therefore a select agent and subject to APHIS' select agent and toxin regulations.