FRONT RIGHT TIRE ON VEHICLE SUDDENLY LOST ALL AIR PRESSURE WHILE TRAVELING DOWN INTERSTATE HIGHWAY FOR UNKNOWN REASONS AND VEHICLE WAS INVOLVED IN A CRASH WITH INJURIES. TIRE WAS IDENTIFIED AS A SAILUN S-825 385/65R22.5 1 MIXED SERVICE WIDE BASE TIRE ON THE FRONT RIGHT AXLE. NO OBJECTS WERE DISCOVERED IN THE ROADWAY THAT COULD HAVE POSSIBLY CAUSED THE RAPID DEFLATION OF THE TIRE. TIRE WAS DESTROYED AFTER DEFLATION AND REMAINED WRAPPED AROUND THE RIM OF THE VEHICLE. MAXIMUM VEHICLE SPEED FOR THE TRIP WAS 49 MPH AND THE TANK ATTACHED TO THE VEHICLE WAS EMPTY AT THE TIME OF THE EVENT.