Yesterday evening, 8/13/2022, I had my family in the F150 TRUCK. We were traveling at 77 mph (in a 70 mph zone) on toll route 576 enroute to Pittsburgh Airport. The F150 TRUCK was on cruise control (this time) when it downshifted from 10th gear to 1st gear. My neck is very sore, now. It continued to mis-shift although no service light illuminated this time. The milage during this incident was 53,809.3 (give or take a mile or two, I don't take pictures when at the wheel of F150 TRUCK) All my family was traumatized again. The truck made it to the airport. Where we picked up our foreign exchange student from Japan named Jua. The ride home, I white knuckled the steering wheel, not knowing when we would go out of control. The truck made it home without causing death to our family or innocent civilians. This is the second time this has occurred. Ford attempted to fix with valve body replacement.