The contact owns a 2014 Ford F-150. The contact stated that while driving at 45 MPH on a two-lane highway, the vehicle seized on low gear and the rear of the vehicle seized. The ABS did not engage to bring the vehicle to a stop, the rear remained seized causing the contact to rear-end the vehicle in front. No air bags deployed. A police report was filed. The contact sustained a fractured finger, head, and back injuries that required medical attention via the hospital. Due to cost, the contact could not continue his medical treatment. The other vehicle was able to be driven from the scene and the occupant sustained unknown injuries that required medical attention but no further information was available. The vehicle was driven home after the crash. The vehicle was taken to an independent mechanic where the frame was repaired and replaced the damaged front end parts. The vehicle was repaired. The contact mentioned that the transmission was previously rebuilt approximately 3-4 years ago with AAMCO due to an undetermined failure with an unexpected downshift into first gear. The vehicle was taken to a dealer where it was serviced for NHTSA Campaign Number: 24V444000 (Power Train). The contact was concerned that the failure would recur. The manufacturer was made aware of the failure and was referred to the NHTSA Hotline. The failure mileage was 150,000.