The contact owns a 2014 Ford F-250. The contact stated that while driving at an undisclosed speed hauling a trailer, the exhaust manifold dropped raw fuel into the exhaust and it caught fire. The contact was able to extinguish the fire. The exhaust filter over maximum limit message was displayed. There were no reported injuries, crash , police report or air bag deployment. The fire department was on the scene. The vehicle was towed to the local dealer, where it was diagnosed and determined that cylinder one was down and the engine and transmission needed to be replaced. The mechanic informed the contact that the EPF may be damaged and not work. The vehicle was not repaired. The manufacturer was contacted, who referred to the NHTSA hotline. The failure mileage was approximately 195,000.